Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling
Literature Reference
Authors:
Eric Schoger, Federico Bleckwedel, Giulia Germena, Cheila Rocha, Petra Tucholla, Izzatullo Sobitov, Wiebke Möbius, Maren Sitte, Christof Lenz, Mostafa Samak, Rabea Hinkel, Zoltán V. Varga, Zoltán Giricz, Gabriela Salinas, Julia C. Gross, Laura C. Zelarayán
Year: 2023
Aberrant Wnt activation has been reported in failing cardiomyocytes. Here we present single cell transcriptome profiling of hearts with inducible cardiomyocyte-specific Wnt activation (β-cat[Δex3] ) as well as with compensatory ...
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