Video drop

<p><img alt="images/Pasted image 20230114160751.png" class="wikiimage" src="/images/pasted image 20230114160751.png" /> (Scheme from [<a class="litnote tooltip" href="/literature/@boccara2016">@boccara2016<span class="tooltiptext">Full-field interferometry for counting and differentiating aquatic biotic nanoparticles: from laboratory to Tara Oceans</span></a>])</p> <p>It exploits an <a class="wikilink" href="/interferometric_detection_schemes/">interferometric detection schemes</a> using a non-coherent light source (an LED) that shines straight through the sample. The interference is created by particles in suspension and the light that went close to them. It sounds like a very smart exploit of having a point-spread function larger than the particles themselves. </p> <p>According to the website, and some superficial discussion during a conference, the secret lays in the fact that the interference that is measured happens at a very specific plane in the sample (is this related to <a class="wikilink" href="/köhler_illumination/">Köhler Illumination</a> in any way?)</p> <p>In the end, the measurement relies on a <a class="wikilink" href="/nanoparticle_tracking_analysis/">nanoparticle tracking analysis</a>, where the largest advantage is that the direct intereference makes it <em>easier</em> to acquire, and in principle it detects particles which are weak scatterers. However, it still suffers from all the <a class="wikilink" href="/limitations_of_nanoparticle_tracking_analysis/">limitations of nanoparticle tracking analysis</a>.</p>