Ultra centrifugations is the most popular ev enrichment method
ultra centrifugation is widely used to enrich extracellular vesicles samples. However, it is only based on the precipitation of heavier elements in a liquid, which is not particularly selective for bio-fluids [@mizenko 2021 citing an ISEV report].
The second most used method is Size exclusion chromatography is the second most popular EV enrichment method.
Also see: Analytical Ultracentrifugation.
These are the other notes that link to this one.