Ultra centrifugations is the most popular ev enrichment method

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ultra centrifugation is widely used to enrich extracellular vesicles samples. However, it is only based on the precipitation of heavier elements in a liquid, which is not particularly selective for bio-fluids [@mizenko 2021 citing an ISEV report].

The second most used method is Size exclusion chromatography is the second most popular EV enrichment method.

Also see: Analytical Ultracentrifugation.


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