Time-based separation methods

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These are particle, molecule, or cell, separation methods that rely on the residence time of the sample to create enrichment.

In size exclusion chromatography, for example, smaller particles stay longer in the column (diffuse slower). Effectively, one would put a given volume on the top, and the same volume would come out from the bottom with a gradient of sizes.

Other methods are: HPLC and Flow induced dispersion analysis.

An alternative are spatial-based separation methods.


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Aquiles Carattino
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